Research Participation Opportunities

Participants should be 8-12 years old with myopia. Their prescription must be between -0.75 to -4.00 with no astigmatism greater than -0.75. There can be no history of myopia control in the past or corneal scars.

This is an FDA-regulated clinical trial that studies the effect of specially design contact lenses in slowing the progression of myopia. These contact lenses have been FDA-approved and now we are doing post market research on the lenses.

Participants will receive an eye exam, where our investigators will check their visual acuity, health of their eye, and evaluate the fit of the contact lenses. They will be dilated at visits, depending on which visit it is. Kids will be asked to fill out a questionnaire about their vision and the quality of their vision. We will measure axial length.

There are 11 scheduled visits over the course of 4 years. The visits will range from 1.5 to 2.5 hours.

Participants will receive a free supply of contact lenses for the duration of the study, eye exams every 6 months, and a check will be mailed to them ranging from $50-$100 depending on the visit.

Lilly Cheam
857-357-4742
[email protected]

Inclusion
patients >18yo with history of stroke;

Exclusion
• Diagnosis of multiple sclerosis or other demyelinating disease (with or without optic neuritis)
• ALS or other degenerative motor neuron disorder diagnoses
• Best-corrected VA <20/40 • Spherical refractive error > +/- 6.00 D
• Refractive error > 2.50 D of astigmatism
• Intra-Ocular Pressure > 21 mmHg
• Presence of RAPD in either eye
• Glaucoma or other Optic Neuropathies
• Retinal Venous Disease
• AREDS Grade 3 AMD
• Congenital/acquired macular diseases

There is a strong connection between neuronal and vascular networks of the eye and the brain. This study will enroll participants with a diagnosis of stroke to participate in retinal imaging to study health of neurons and vessels in the eye.

Study participants will undergo dilated non-invasive retinal imaging, such as fundus photography, to investigate the health of retinal neuronal and vascular networks.

Visit(s): 1
Length: 1-1.5 hrs

The participant will be compensated $50.

Cecilia Idman-Rait
617-519-1591
[email protected]

1. Age 65 and over
2. No history of ocular surgery, with the exception of cataract surgery (unless monovision was the result of cataract surgery)
3. No history of ocular disease
4. No current use of any ocular medications (excluding artificial tears)

This study will explore visual changes that occur with healthy aging, which may help us better understand how to help older adults function in their daily lives.

Participants will complete a quick demographic questionnaire and survey about their sleep-wake cycle, as well as have their vision (i.e., visual acuity and optical prescription) and the anatomy of their eye (e.g., eye length) measured with standard non-invasive clinical devices.  Participants will then perform several psychophysical tasks on a standard computer monitor.

3 visits over the span of 2 weeks. Visits range from 1-2 hours.

The participant will be compensated $30 per visit ($90 total for all 3 visits).

Yaffa Kizel
[email protected]

Christopher Taylor
[email protected]

1. Participants should be 4-12 years of age with amblyopia in one eye.
2. Vision in the amblyopic eye should be 20/40 to 20/200 (3+ line difference from the better seeing eye).
3. Prior treatment is ok (Atropine eye drops or patching), the study doctors will discuss when these must be discontinued in order to be enrolled.

Amblyopia is one of the most common causes of decreased vision in children and affects approximately 2-3% of children. A new treatment for amblyopia is binocular game therapy. These studies are multicenter randomized clinical trials designed to evaluate the effectiveness of these new treatments in young children with amblyopia in one eye.

National Institutes of Health / National Eye Institute: 2UG1EY011751

Registered at ClinicalTrials.gov – Identifiers: NCT06380517 and NCT06524882

Participants will receive an eye exam where the investigators will check vision in glasses, and check if there are changes needed to the prescription glasses that have been previously provided by their eye doctor. If a change in glasses is needed, the child will be dilated.

Children and their parent/guardian will be asked to fill out a questionnaire about their vision and the quality of life related to vision.

A computer program will be used to decide whether your child will start the study wearing glasses alone, wearing an eye patch (2 hours a day, 7 days a week), watching shows using the Luminopia virtual reality headset (1 hour a day, 6 days a week) or playing games using the Vivid Vision virtual reality headset (25 minutes per day, 6 days per week).

ATS 23 (4-7 year olds): 26 weeks with optional crossover up to 52 weeks

• After the enrollment visit, there are two follow-up visits at 13 weeks and 26 weeks after the first visit.
• If your child starts the study with patching, they will have the opportunity to try the Luminopia headset for 26 weeks if they still have amblyopia (with follow-ups at 39 weeks and 52 weeks).

ATS 24 (8-12 year olds): 18 weeks with optional crossover up to 36 weeks

• After the enrollment visit, there are two follow-up visits at 9 weeks and 18 weeks after the first visit. If your child starts the study with glasses alone, they will have the opportunity to try the Luminopia headset for 18 weeks if they still have amblyopia (with follow-ups at 27 weeks and 36 weeks).

Participants will receive patches, the virtual reality headsets, and any new glasses needed during the study at no cost. The headset will need to be returned to your study doctor when the study ends. To cover travel and other visit-related expenses, you will be paid $100 for completing each follow-up exam, up to $500.

ATS 23 (4-7 year olds):
Dr. Kristen Kerber
[email protected]

ATS 24 (8-12 year olds):
Dr. Katherine Green
[email protected]