Please join Bas Rokers, Brain and Cognition Sciences, MIT and Department of Psychology, University of Wisconsin - Madison, for a presentation entitled “Altered white matter in early visual pathways as a result of amblyopia.” The lecture will take place on November 17th as part of the Research Lecture Series. All are welcome to attend. One hour of Mass CE credit will be offered.
Abstract: Amblyopia is a visual disorder caused by poorly coordinated binocular input during development, and the leading cause of vision loss amongst children. Little is known about the impact of amblyopia on the white matter within the visual system. We studied the properties of six major visual white-matter pathways in a group of adults with amblyopia (n = 10) and matched controls (n = 10) using diffusion weighted imaging (DWI) and fiber tractography. While we did not find significant differences in diffusion properties in cortico-cortical pathways, patients with amblyopia exhibited increased mean diffusivity in thalamo-cortical visual pathways. These findings suggest that amblyopia may systematically alter the white matter properties of early visual pathways, and may provide new avenues for the diagnosis and treatment of visual disorders with a neural basis.